---
title: Utility of an Automated Artificial Intelligence Echocardiography Software in Risk Stratification of Hospitalized COVID-19 Patients.
description: Utility of an Automated Artificial Intelligence Echocardiography Software in Risk Stratification of Hospitalized COVID-19 Patients.
---

[Proof ](https://www.ultromics.com/proof)

# [Utility of an Automated Artificial Intelligence Echocardiography Software in Risk Stratification of Hospitalized COVID-19 Patients.](https://www.ultromics.com/proof/utility-of-an-automated-artificial-intelligence-echocardiography-software-in-risk-stratification-of-hospitalized-covid-19-patients)

 Written by [Ultromics](https://www.ultromics.com/proof/author/ultromics) | May 3, 2021 11:16:00 AM

*Wang et al. J Am Coll Cardiol. 2021.*

Cardiovascular disease, risk factors, and elevated biomarkers are associated with poor prognosis in COVID-19 infections. Significant progress in artificial intelligence (AI) applied to cardiac imaging have recently been made. We assessed the utility of an AI analytic software called EchoGo (by Ultromics) in COVID-19 inpatients. 

Fifty consecutive COVID-19 positive inpatients (mean age 66±13 years, 22 women) undergoing echocardiography in 4/17/2020-8/5/2020 were analyzed with EchoGo software. Left ventricular end-diastolic volume (LVEDV), end-systolic volume (LVESV), ejection fraction (LVEF) and global longitudinal strain (LVGLS) were correlated with standard echocardiography measurements. After adjustment for APACHE-4 score, associations with clinical outcomes were assessed (death, mechanical ventilation, and acute myocardial injury).

Mean EchoGo outputs were LVEDV 121±42 mL, LVESV 53±30 mL, LVEF 58±11%, and LVGLS -16.1±5.1%. Their Pearson correlation coefficients (P-value) with standard measurements were 0.810 (<0.001), 0.873 (<0.001), 0.528 (<0.001) and 0.690 (<0.001). The primary endpoint occurred in 26 (52%) patients: 8 (16%) deaths, 16 (32%) mechanical ventilation and 21 (42%) acute myocardial injury. Adjusting for APACHE-4 score, EchoGo LVEF and LVGLS were associated with the primary endpoint (Figure). 

## **Conclusion**

Automated AI softwares are new clinical tools that may assist with patient care. EchoGo LVEF and LVGLS were associated with adverse outcomes in hospitalized COVID-19 patients and can play a role in their risk stratification. 

Full study: [https://www.jacc.org/doi/10.1016/S0735-1097%2821%2904444-2](https://www.jacc.org/doi/10.1016/S0735-1097%2821%2904444-2) 

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